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[...] Pharmacy Express (hereafter referred to in this document as PE) is a very large and sophisticated spamming operation believed to be operated by the Russian criminal spammer Leo Kuvayev, and several of his colleagues and affiliates. These sites have been spamvertised relentlessly to several million email addresses since at least 2004, possibly even longer. Mr. Kuvayev is wanted for several international charges which he has never answered for, including money laundering, child porn and of course illegal spamming. This spam operation has numerous ties to several large-scale Windows viruses and Trojan infections dating back numerous years. The botnets alleged to be behind this operation handle everything from domain registration to zombie infection to probably website hosting and "order" processing. Nobody has ever claimed to have received any quality assured medications upon ordering, so this series of websites is actually considered a credit card fraud operation very similar to Alex Polyakov's My Canadian Pharmacy. [...]